Professor David Torpy is a Consultant Endocrinologist at the Royal Adelaide Hospital. His research interests predominantly involve studies of the hypothalamic-pituitary-adrenal axis and stress. Recent specific areas have included corticosteroid-binding globulin (CBG) genetic variants and their effect on the stress response, immune-HPA interactions involving CBG in inflammatory states, adrenal function in septic shock, maternal cortisolaemia in complicated pregnancies, inherited forms of adrenal dysfunction causing Cushing’s, adrenocortical carcinoma, opioids and adrenal function, the stress axis in hypoglycaemia unawareness, and cortisone dosing and well-being in Addison’s disease.